@ARTICLE{Portet2009,
  author = {St{\'e}phanie Portet and Julien Arino},
  title = {An in vivo intermediate filament assembly model.},
  journal = {Mathematical Biosciences and Engineering},
  year = {2009},
  volume = {6},
  pages = {117--134},
  number = {1},
  month = {Jan},
  abstract = {A model is developed to study the in vivo intermediate filament organization
	in terms of repartition between four different structural states:
	soluble proteins, particles, short, and long filaments. An analysis
	is conducted, showing that the system has a unique, globally asymptotically
	stable equilibrium. By means of sensitivity analysis, the influence
	of parameters on the system is studied. It is shown that, in agreement
	with biological observations, posttranslational modifications of
	intermediate filament proteins resulting in filament solubilization
	are the main regulators of the intermediate filament organization.
	A high signalling-dependent solubilization of filaments favours the
	intermediate filament aggregation in particles.},
  institution = {Department of Mathematics, University of Manitoba, Winnipeg, MB,
	Canada. portets@cc.umanitoba.ca},
  keywords = {Animals; Computer Simulation; Cytoskeletal Proteins, physiology; Cytoskeleton,
	physiology; Humans; Models, Biological; Signal Transduction, physiology},
  language = {eng},
  medline-pst = {ppublish},
  owner = {sportet},
  pmid = {19292511},
  timestamp = {2013.11.13}
}